منابع مشابه
Local Anesthetics Properties of Local Anesthetics
The first clinical uses of a local anesthetic agent occurred in 1884, when cocaine was employed as a topical agent for eye surgery and to produce a nerve block. These events inaugurated a new era, that of regional anesthesia. New applications were developed, including spinal, epidural, and caudal anesthesia. The search for a better local anesthetic led to chemical synthesis of a number of other...
متن کاملToxicity of local anesthetics
Systemic neurotoxicity due to excessive cerebral local anesthetic blood levels is one of the most severe and most frequent adverse outcome of local anesthetic use. Toxic levels are most often produced by unintentional intravenous or intraarterial injection(1,2). Toxicity can also result from the rapid absorption of drug following perineural injection. Peak blood levels are usually obtained acco...
متن کاملMechanisM of LocaL anesthetics
Local anesthetic systemic toxicity (LAST) is a rare yet devastating complication from the administration of local anesthesia. The ability to recognize and treat LAST is critical for clinicians who administer these drugs. The authors reviewed the literature on the mechanism, treatment, and prevention of LAST, with the goal of proposing a practical method for its management.
متن کاملChapter 11 - Local Anesthetics
QUESTIONS OF THE DAY L ocal anesthesia can be defined as loss of sensation in a discrete region of the body caused by disruption of impulse generation or propagation. Local anesthesia can be produced by various chemical and physical means. However, in routine clinical practice, local anesthesia is produced by a narrow class of compounds, and recovery is normally spontaneous, predictable, and co...
متن کاملC Local anesthetics
Purpose of review Local anesthetics are used in a wide range of clinical situations to prevent acute pain and to stop or ameliorate pain produced by cancer or pain associated with chronic painful conditions. Knowledge of the pharmacology of local anesthetics is essential for their safe use and selection of specific agents to achieve intended goals. Recent findings Local anesthetics are a group ...
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ژورنال
عنوان ژورنال: Anais Brasileiros de Dermatologia
سال: 2020
ISSN: 0365-0596
DOI: 10.1016/j.abd.2019.09.025